Multi-gentre

I've written mystery fantasy. I've written urban fantasy. I've written fantasy (though the less said about that particular work, the better). I've written a partial for a spy story (it may never see life outside of the drawer, but I still wrote it). I've begun a historical mystery. I'm about to begin a sci-fi space opera.
I can't help but wonder if I'm in too many genres. Will agents, publishers, and readers accept someone who writes so much scattered across the genre board? I know pen names can help, but those are short-lived in the age of social networking.
Of course, that's a conversation to have once I get an agent, so I guess I should shut up and get back to writing.
But part of me can't help but think about it from time to time.